Treat Yourself to a Fantastic South America Cruise

Experience the Pleasures of a South America Cruise

South America cruises with Orbitz offer the utmost in vacation fun and leisure, from one end of the continent to the other.

Set sail to the west coast city of Cartagena, Columbia, and experience the thrill of walking through the old, Spanish-colonial streets of downtown, immersed with authentic restaurants, shops and exquisite architecture. Colon, Panama offers an incredible shot of the Panama Canal, a 48-mile waterway which connects the Pacific and Atlantic Oceans. Arica, Chile is a port stationed on the Pacific coast and known for its beautiful and radiant beaches.

To the far east of South America, we’ll take you to the breathtaking beaches of Santos (Sao Paulo) or Ilhabela, the “Salt Capital” of Brazil. Discover the ancient artifacts and shipwrecked vessels resting at the bottom of the sea, just off the coast. For a more lively experience, visit Buzios and get down with their vivacious nightlife which includes discos, nightclubs and dynamic restaurants.

Don’t forget the beauty and charm of the country of Uruguay, a haven for spectacular cruise ports like Punta del Este and Montevideo; both exhibit extraordinary beaches, incredible surf and, on shore, a multitude of fun and exuberant tourist activities.

Book your South America cruise adventure with Orbitz, and you’re sure to take home memories of a vacation experience you will never forget.



Brochure price $3,399 – Save up to 71%
3.8 / 5  (249 reviews)


Departing from: Valparaiso (Santiago), Chile
Ports of Call: Valparaiso (Santiago), Chile • Coquimbo (La Serena), Chile • General San Martin (Pisco), Peru • Callao (Lima), Peru • Salaverry (Trujillo), Peru • Manta, Ecuador • Puerto Caldera (Puntarenas), Costa Rica • Puerto Chiapas (Tapachula), Mexico • Cabo San Lucas, Mexico • San Diego, California
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Bonus Offers Available:
  • CALL: Up to $700 Savings - Coupon Booklets!
  • CALL: Up to $700 Savings - Coupon Booklets!
    Call to book ANY stateroom on a qualifying Holland America sailing, and we will give you an Onboard Savings Booklet per person (maximum of 2); each are worth up to $350 in savings. Some restrictions apply - new bookings only. Offer ends 11:59 pm ET on 3/31/17!
  • Limited Time Reduced Rates!
  • Limited Time Reduced Rates!
    Limited time reduced rates - hurry these rates won't last long! This offer is valid for new reservations only, certain restrictions may apply. This rate is non-refundable and not combinable with other cruise line promotions.
  • CALL: Up to $150 FREE Onboard Spending!
  • CALL: Up to $150 FREE Onboard Spending!
    Call to book your cruise vacation on select 2017 and 2018 Holland America sailings and you may be eligible to receive up to $150 FREE onboard credit. Onboard credit amount is based on length of sailing, category purchased and valid for new reservations only. Credit can be used to purchase beverages or other onboard amenities. Not all fares displaying online qualify for this offer please call for more details and to book your vacation. Hurry offer ends 11:59 pm ET on 3/31!
  • CALL: Up to $100 FREE Onboard Spending!
  • CALL: Up to $100 FREE Onboard Spending!
    Call to book any stateroom on a qualifying Holland America sailing departing between 1/3/17 and 11/29/17, and we will give you up to $100 FREE onboard spending; amount varies by sailing! Hurry - limited space available.
  • Earn Unlimited Future Cruise Credits for Referrals!
  • Earn Unlimited Future Cruise Credits for Referrals!
    Each time you refer a new customer to us, we will give you a $50 Future Cruise Credit after their sailing departs. There is no limit to the number of Future Cruise Credits earned, and you can apply them toward your next booking with us. Simply have your referral call us to book, indicate that you recommended us, and provide us with your name and city/state or email address. Offer is not valid if the referred customer is traveling aboard the same sailing as you.
About South America
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Terms & Conditions
Total cruise prices listed are samples in U.S. dollars of select stateroom category types as indicated and include non-commissionable fares. All prices and bonus offers are valid only for new individual bookings for select stateroom categories on select sailings aboard select cruise lines. Total cruise prices include government taxes and fees, airfare, and a non-refundable $24.99 processing fee per booking. Minimum hotel costs apply as follows: $250 for the $75 promo code, $300 for the $100 promo code, $400 for the $150 promo code, $475 for the $200 promo code, $550 for the $300 promo code, and $750 for the $500 promo code, $1,000 for the $750 hotel promo code and $1,250 for the $1,000 hotel promo code. Cancellation penalties, blackout dates, and other restrictions may apply. Total cruise prices and bonus offers vary by departure date and city, sailing, ship, and stateroom category selected and are subject to availability, capacity-controlled, limited by each cruise line, may not be combinable with other offers, and may be changed or withdrawn at any time without notice. All reservations must be made in U.S. dollars; restrictions may apply for non-U.S. residents. Full Terms & Conditions. Best Price Guarantee restrictions and instructions apply; see our Best Rate Guarantee Policy.

Special requirements
If you or a guest is pregnant or traveling with an infant child, or if there is a need to communicate a request for special meals, medical conditions or physical challenges, we ask that you please call 888-656-8184. Cruise Specialists are available 24 hours a day, 7 days a week. We will do everything we can to meet your needs and answer all of your questions.

Minimum age requirements may apply.
Free upgrade!

Book an eligible stateroom on any qualifying sailing and receive a free upgrade! In some cases, you'll be upgraded to a more desirable location aboard your ship. In other instances, you'll be upgraded to a stateroom with extra space and/or a better view. It's also possible that you might receive all of these benefits. Select your sailing date to see which upgrades are available.

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