Cheap South America cruises at Orbitz
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Treat Yourself to a Fantastic South America Cruise

Experience the Pleasures of a South America Cruise

South America cruises with Orbitz offer the utmost in vacation fun and leisure, from one end of the continent to the other.

Set sail to the west coast city of Cartagena, Columbia, and experience the thrill of walking through the old, Spanish-colonial streets of downtown, immersed with authentic restaurants, shops and exquisite architecture. Colon, Panama offers an incredible shot of the Panama Canal, a 48-mile waterway which connects the Pacific and Atlantic Oceans. Arica, Chile is a port stationed on the Pacific coast and known for its beautiful and radiant beaches.

To the far east of South America, we’ll take you to the breathtaking beaches of Santos (Sao Paulo) or Ilhabela, the “Salt Capital” of Brazil. Discover the ancient artifacts and shipwrecked vessels resting at the bottom of the sea, just off the coast. For a more lively experience, visit Buzios and get down with their vivacious nightlife which includes discos, nightclubs and dynamic restaurants.

Don’t forget the beauty and charm of the country of Uruguay, a haven for spectacular cruise ports like Punta del Este and Montevideo; both exhibit extraordinary beaches, incredible surf and, on shore, a multitude of fun and exuberant tourist activities.

Book your South America cruise adventure with Orbitz, and you’re sure to take home memories of a vacation experience you will never forget.

South America Cruises
Fall Savings Event
Huge savings on all fleets, bonus deals & more!

SOUTH AMERICA CRUISE DEALS
SOUTH AMERICA CRUISE DEALS
3.9 / 5  (460 reviews)

Rhapsody of the Seas

Departing from: Santos (Sao Paulo), Brazil
Ports of Call: Santos (Sao Paulo), Brazil • Punta Del Este, Uruguay • Buenos Aires, Argentina • Montevideo, Uruguay • Santos (Sao Paulo), Brazil
interior from
$891
$127/night
oceanview from
$846
$121/night
balcony from
$1,567
$224/night
suite from
$1,820
$260/night
3.8 / 5  (383 reviews)

Celebrity Infinity

Departing from: Ft. Lauderdale (Port Everglades), Florida
Ports of Call: Ft. Lauderdale (Port Everglades), Florida • Cartagena, Colombia • Colon, Panama • Panama Canal Full Transit • Manta, Ecuador • Callao (Lima), Peru • Arica, Chile • Valparaiso (Santiago), Chile
interior from
$899
$60/night
oceanview from
$1,049
$70/night
balcony from
$1,599
$107/night
suite from
$2,949
$197/night
Brochure price $2,849 – Save up to 58%
3.7 / 5  (213 reviews)

Zaandam

Departing from: Buenos Aires, Argentina
Ports of Call: Buenos Aires, Argentina • Montevideo, Uruguay • Port Stanley, Falkland Islands • Cruise Strait Of Magellan • Punta Arenas, Chile • Cruise Cockburn Channel • Cruise Beagle Channel • Cruise Glacier Alley • Ushuaia, Tierra Del Fuego, Argentina • Cruise Cape Horn • Cruise Canal Sarmiento • Cruise Chilean Fjords • Puerto Montt, Chile • Valparaiso (Santiago), Chile
interior from
$1,199
$86/night
oceanview from
$1,299
$93/night
balcony from
$2,399
$171/night
suite from
$4,499
$321/night
3.7 / 5  (298 reviews)

Star Princess

Departing from: San Pedro (Los Angeles), California
Ports of Call: San Pedro (Los Angeles), California • Cabo San Lucas, Mexico • San Juan Del Sur, Nicaragua • Puntarenas, Costa Rica • Callao (Lima), Peru • General San Martin (Pisco), Peru • Coquimbo (La Serena), Chile • Valparaiso (Santiago), Chile
interior from
$999
$59/night
oceanview from
$1,559
$92/night
balcony from
$1,899
$112/night
suite from
$2,399
$141/night
Brochure price $2,849 – Save up to 61%
3.7 / 5  (213 reviews)

Zaandam

Departing from: Valparaiso (Santiago), Chile
Ports of Call: Valparaiso (Santiago), Chile • Puerto Montt, Chile • Puerto Chacabuco, Chile • Cruise Chilean Fjords • Cruise Canal Sarmiento • Cruise Strait Of Magellan • Punta Arenas, Chile • Cruise Cockburn Channel • Cruise Beagle Channel • Cruise Glacier Alley • Ushuaia, Tierra Del Fuego, Argentina • Cruise Cape Horn • Stanley, Falkland Islands • Montevideo, Uruguay • Buenos Aires, Argentina
interior from
$1,099
$79/night
oceanview from
$1,199
$86/night
balcony from
$2,199
$157/night
suite from
$4,499
$321/night
Brochure price $2,999 – Save up to 67%
3.5 / 5  (995 reviews)

Norwegian Sun

Departing from: Buenos Aires, Argentina
Ports of Call: Buenos Aires, Argentina • Montevideo, Uruguay • Puerto Madryn, Argentina • Port Stanley, Falkland Islands • Cruise Cape Horn • Ushuaia, Tierra Del Fuego, Argentina • Cruise Beagle Channel • Punta Arenas, Chile • Cruise Strait Of Magellan • Cruise Chilean Fjords • Cruise Patagonic Channel • Cruise Canal Moraleda • Puerto Chacabuco, Chile • Puerto Montt, Chile • Valparaiso (Santiago), Chile
interior from
$999
$71/night
oceanview from
$1,349
$96/night
balcony from
$1,999
$143/night
suite from
$3,599
$257/night
Brochure price $2,999 – Save up to 60%
3.5 / 5  (995 reviews)

Norwegian Sun

Departing from: Valparaiso (Santiago), Chile
Ports of Call: Valparaiso (Santiago), Chile • Puerto Montt, Chile • Puerto Chacabuco, Chile • Cruise Patagonic Channel • Cruise Chilean Fjords • Cruise Strait Of Magellan • Punta Arenas, Chile • Cruise Beagle Channel • Ushuaia, Tierra Del Fuego, Argentina • Cruise Cape Horn • Port Stanley, Falkland Islands • Puerto Madryn, Argentina • Montevideo, Uruguay • Buenos Aires, Argentina
interior from
$1,199
$86/night
oceanview from
$1,549
$111/night
balcony from
$2,129
$152/night
suite from
$3,839
$274/night
Brochure price $3,439 – Save up to 54%
3.7 / 5  (126 reviews)

Amsterdam

Departing from: Callao (Lima), Peru
Ports of Call: Callao (Lima), Peru • General San Martin (Pisco), Peru • Puerto Caldera, Costa Rica • Puerto Corinto, Nicaragua • Puerto Quetzal, Guatemala • Zihuatanejo/Ixtapa, Mexico • Manzanillo, Mexico • Puerto Vallarta, Mexico • San Diego, California
interior from
$1,599
$100/night
oceanview from
$1,599
$100/night
balcony from
Call
suite from
$5,399
$337/night
3.9 / 5  (460 reviews)

Rhapsody of the Seas

Departing from: Santos (Sao Paulo), Brazil
Ports of Call: Santos (Sao Paulo), Brazil • Porto Belo, Brazil • Ilhabela, Brazil • Buzios, Brazil • Rio De Janeiro, Brazil • Cruise Copacabana Beach, Brazil • Ilha Grande, Brazil • Santos (Sao Paulo), Brazil
interior from
$1,446
$181/night
oceanview from
$1,704
$213/night
balcony from
$3,119
$390/night
suite from
$3,972
$497/night
Brochure price $3,599 – Save up to 72%
3.5 / 5  (995 reviews)

Norwegian Sun

Departing from: San Diego, California
Ports of Call: San Diego, California • Huatulco, Mexico • Puerto Chiapas (Tapachula), Mexico • Puerto Quetzal, Guatemala • Puntarenas, Costa Rica • Salaverry (Trujillo), Peru • Callao (Lima), Peru • Arica, Chile • Coquimbo (La Serena), Chile • Valparaiso (Santiago), Chile
interior from
$999
$59/night
oceanview from
$1,299
$76/night
balcony from
$1,999
$118/night
suite from
$3,499
$206/night
Bonus Offers Available:
3.8 / 5  (383 reviews)

Celebrity Infinity

Departing from: Valparaiso (Santiago), Chile
Ports of Call: Valparaiso (Santiago), Chile • Puerto Montt, Chile • Cruise Chilean Fjords • Cruise Strait Of Magellan • Punta Arenas, Chile • Ushuaia, Tierra Del Fuego, Argentina • Cruise Cape Horn • Puerto Madryn, Argentina • Punta Del Este, Uruguay • Montevideo, Uruguay • Buenos Aires, Argentina
interior from
$1,549
$111/night
oceanview from
$2,049
$146/night
balcony from
$3,449
$246/night
suite from
$7,199
$514/night
Brochure price $3,699 – Save up to 68%
3.7 / 5  (213 reviews)

Zaandam

Departing from: San Diego, California
Ports of Call: San Diego, California • Puerto Vallarta, Mexico • Huatulco, Mexico • Puerto Chiapas (Tapachula), Mexico • Puerto Quetzal, Guatemala • Manta, Ecuador • Salaverry (Trujillo), Peru • Callao (Lima), Peru • Coquimbo (La Serena), Chile • Valparaiso (Santiago), Chile
interior from
$1,199
$67/night
oceanview from
$1,299
$72/night
balcony from
$2,699
$150/night
suite from
$6,899
$383/night
Brochure price $8,198 – Save up to 76%
3.8 / 5  (29 reviews)

Marina

Departing from: Rio De Janeiro, Brazil
Ports of Call: Rio De Janeiro, Brazil • Buzios, Brazil • Ilha Grande, Brazil • Parati, Brazil • Santos (Sao Paulo), Brazil • Porto Belo, Brazil • Rio Grande, Brazil • Punta Del Este, Uruguay • Montevideo, Uruguay • Buenos Aires, Argentina
interior from
$1,999
$200/night
oceanview from
$2,799
$280/night
balcony from
$3,399
$340/night
suite from
$5,099
$510/night
Brochure price $15,990 – Save up to 59%
4.7 / 5  (34 reviews)

Crystal Symphony

Departing from: San Juan, Puerto Rico
Ports of Call: San Juan, Puerto Rico • Scarborough, Tobago • Devils Island, French Guiana • Fortaleza, Brazil • Recife, Brazil • Salvador De Bahia, Brazil • Rio De Janeiro, Brazil • Buzios, Brazil • Rio De Janeiro, Brazil
interior from
N/A
oceanview from
$6,495
$433/night
balcony from
$9,765
$651/night
suite from
Call
Brochure price $29,598 – Save up to 61%
3.9 / 5  (30 reviews)

Seven Seas Navigator

Departing from: Miami, Florida
Ports of Call: Miami, Florida • Gustavia, St. Barts • Castries, St. Lucia • St. George's, Grenada • Port Of Spain, Trinidad • Macapa (Amazon River), Brazil • Santarem (Amazon River), Brazil • Boca Da Valeria (Amazon River), Brazil • Manaus (Amazon River), Brazil • Parintins (Amazon River), Brazil • Alter Do Chao (Amazon River), Brazil • Macapa (Amazon River), Brazil • Devils Island, French Guiana • Bridgetown, Barbados • St. John's, Antigua • San Juan, Puerto Rico • Miami, Florida
interior from
N/A
oceanview from
N/A
balcony from
N/A
suite from
$11,599
$464/night
About South America
 
South America
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Terms & Conditions
Total cruise prices listed are samples in U.S. dollars of select stateroom category types as indicated and include non-commissionable fares. All prices and bonus offers are valid only for new individual bookings for select stateroom categories on select sailings aboard select cruise lines. Total cruise prices include government taxes and fees, airfare, and a non-refundable $24.99 processing fee per booking. Minimum hotel costs apply as follows: $250 for the $75 promo code, $300 for the $100 promo code, $400 for the $150 promo code, $475 for the $200 promo code, $550 for the $300 promo code, and $750 for the $500 promo code, $1,000 for the $750 hotel promo code and $1,250 for the $1,000 hotel promo code. Cancellation penalties, blackout dates, and other restrictions may apply. Total cruise prices and bonus offers vary by departure date and city, sailing, ship, and stateroom category selected and are subject to availability, capacity-controlled, limited by each cruise line, may not be combinable with other offers, and may be changed or withdrawn at any time without notice. All reservations must be made in U.S. dollars; restrictions may apply for non-U.S. residents. Full Terms & Conditions. Best Price Guarantee restrictions and instructions apply; see our Best Rate Guarantee Policy.

Special requirements
If you or a guest is pregnant or traveling with an infant child, or if there is a need to communicate a request for special meals, medical conditions or physical challenges, we ask that you please call 888-656-8184. Cruise Specialists are available 24 hours a day, 7 days a week. We will do everything we can to meet your needs and answer all of your questions.

Minimum age requirements may apply.

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