Treat Yourself to a Fantastic South America Cruise

Experience the Pleasures of a South America Cruise

South America cruises with Orbitz offer the utmost in vacation fun and leisure, from one end of the continent to the other.

Set sail to the west coast city of Cartagena, Columbia, and experience the thrill of walking through the old, Spanish-colonial streets of downtown, immersed with authentic restaurants, shops and exquisite architecture. Colon, Panama offers an incredible shot of the Panama Canal, a 48-mile waterway which connects the Pacific and Atlantic Oceans. Arica, Chile is a port stationed on the Pacific coast and known for its beautiful and radiant beaches.

To the far east of South America, we’ll take you to the breathtaking beaches of Santos (Sao Paulo) or Ilhabela, the “Salt Capital” of Brazil. Discover the ancient artifacts and shipwrecked vessels resting at the bottom of the sea, just off the coast. For a more lively experience, visit Buzios and get down with their vivacious nightlife which includes discos, nightclubs and dynamic restaurants.

Don’t forget the beauty and charm of the country of Uruguay, a haven for spectacular cruise ports like Punta del Este and Montevideo; both exhibit extraordinary beaches, incredible surf and, on shore, a multitude of fun and exuberant tourist activities.

Book your South America cruise adventure with Orbitz, and you’re sure to take home memories of a vacation experience you will never forget.

SOUTH AMERICA CRUISE DEALS

SOUTH AMERICA CRUISE DEALS

Brochure price $3,199 – Save up to 69%
3.8 / 5  (245 reviews)

Zaandam

Departing from: Buenos Aires, Argentina
Ports of Call: Buenos Aires, Argentina • Montevideo, Uruguay • Port Stanley, Falkland Islands • Cruise Strait Of Magellan • Punta Arenas, Chile • Cruise Cockburn Channel • Cruise Beagle Channel • Cruise Glacier Alley • Ushuaia, Tierra Del Fuego, Argentina • Cruise Cape Horn • Cruise Canal Sarmiento • Cruise Chilean Fjords • Puerto Montt, Chile • Valparaiso (Santiago), Chile
interior from
$999
$71/night
oceanview from
$1,099
$79/night
balcony from
$1,999
$143/night
suite from
$3,999
$286/night
Bonus Offers Available:
  • CALL: Up to $100 FREE Onboard Spending!
  • CALL: Up to $100 FREE Onboard Spending!
    Call to book any stateroom on a qualifying Holland America sailing departing between 7/3/16 and 12/7/16, and we will give you up to $100 FREE onboard spending; amount varies by sailing! Hurry - limited space available.
  • CALL: Up to $150 FREE Onboard Spending!
  • CALL: Up to $150 FREE Onboard Spending!
    Call to book your cruise vacation on select Holland America sailings departing now through 2018, and you may be eligible to receive up to $150 FREE onboard spending. Onboard spending amount is based on length of sailing, category purchased and valid for new reservations only. Not all fares displaying online qualify for this offer; please call for more details and to book your vacation. Hurry offer ends 11:59 pm ET on 10/3/16!
  • CALL: Up to $350 Savings - Coupon Booklet!
  • CALL: Up to $350 Savings - Coupon Booklet!
    Call to book ANY stateroom on a qualifying Holland America sailing and we will give you an Onboard Savings Booklet worth up to $350. Some restrictions apply - new bookings only. Offer ends 11:59 pm ET on 10/3/16 !
  • Call to Book: Explore4 - Free Drinks, Dining, more
  • Call to Book: Explore4 - Free Drinks, Dining, more
    Call to book your cruise vacation on a select 2017 Holland America sailing and you may be eligible to receive a FREE Signature Beverage Package (up to a $1,400 value), FREE Pinnacle Grill Dinner (a $58 value), and FREE or reduced 3rd-4th guests cruise fares. Book a suite and also receive up to $200 internet credit per stateroom and FREE prepaid gratuities for 2. Restrictions apply - not all pricing displaying online qualifies new bookings only, subject to availability.
  • Earn Unlimited Future Cruise Credits for Referrals!
  • Earn Unlimited Future Cruise Credits for Referrals!
    Each time you refer a new customer to us, we will give you a $50 Future Cruise Credit after their sailing departs. There is no limit to the number of Future Cruise Credits earned, and you can apply them toward your next booking with us. Simply have your referral call us to book, indicate that you recommended us, and provide us with your name and city/state or email address. Offer is not valid if the referred customer is traveling aboard the same sailing as you.
  • Up To $500 Onboard Credit!
  • Up To $500 Onboard Credit!
    For a limited time only, receive up to $500 to spend onboard for liquor, beverages, dining, spa or shore excursions! Simply book a qualifying voyage online or over the phone! Offer is per stateroom, varies based on the price of cruise minus taxes and port charges, is not reflected in advertised prices, and will not exceed $500. Cruises between $750 - $1500 receive $25 OBC. Cruises between $1500 - $2500 receive $50 OBC. Cruises between $2500 - $3500 receive $75 OBC Cruises between $3500 - $4500 receive $100 OBC. Cruises between $4500 - $5500 receive $150 OBC. Cruises between $5500 - $7500 receive $200 OBC. Cruises between $7500 - $10000 receive $250 OBC. Cruises over $10,001 receive $500 OBC.
Brochure price $3,399 – Save up to 72%
3.5 / 5  (1,160 reviews)

Norwegian Sun

Departing from: Valparaiso (Santiago), Chile
Ports of Call: Valparaiso (Santiago), Chile • Puerto Montt, Chile • Puerto Chacabuco, Chile • Cruise Patagonic Channel • Cruise Chilean Fjords • Cruise Strait Of Magellan • Punta Arenas, Chile • Cruise Beagle Channel • Ushuaia, Tierra Del Fuego, Argentina • Cruise Cape Horn • Port Stanley, Falkland Islands • Puerto Madryn, Argentina • Montevideo, Uruguay • Buenos Aires, Argentina
interior from
$949
$68/night
oceanview from
$1,299
$93/night
balcony from
$2,499
$179/night
suite from
$3,399
$243/night
Bonus Offers Available:
  • CHOOSE 1: Free Drinks, Free Gratuities and More
  • CHOOSE 1: Free Drinks, Free Gratuities and More
    Call to book a studio or inside stateroom category on select Norwegian Cruise line sailings and you can choose between an Ultimate Beverage package for 2, a Specialty Dining package, a 250 minute internet package or pre-paid service charges. This offer is for new reservations only. NOT VALID FOR ALL FARES DISPLAYING ONLINE AND IS RESTRICTED TO CERTAIN FARE CODES. Not valid for category IX. Please call to book and for more information. Offer ends 11:59 pm EST on 10/02/16.
  • CHOOSE 2: Free Drinks, Free Gratuities and More
  • CHOOSE 2: Free Drinks, Free Gratuities and More
    Call to book an oceanview, balcony or mini-suite category stateroom on select Norwegian sailings and you can choose two of the following amenities: an Ultimate Beverage package for 2, a Specialty Dining package, a 250 minute internet package or pre-paid service charges. This offer is for new reservations only. NOT VALID FOR ALL FARES DISPLAYING ONLINE AND IS RESTRICTED TO CERTAIN FARE CODES. Not valid for categories OX, BX or MX. Please call to book and for more information. Offer ends 11:59 pm EST on 10/02/16.
  • Earn Unlimited Future Cruise Credits for Referrals!
  • Earn Unlimited Future Cruise Credits for Referrals!
    Each time you refer a new customer to us, we will give you a $50 Future Cruise Credit after their sailing departs. There is no limit to the number of Future Cruise Credits earned, and you can apply them toward your next booking with us. Simply have your referral call us to book, indicate that you recommended us, and provide us with your name and city/state or email address. Offer is not valid if the referred customer is traveling aboard the same sailing as you.
  • Haven & Suites Get 4: FREE Drinks, Dining & More!
  • Haven & Suites Get 4: FREE Drinks, Dining & More!
    Call to book a Haven Suite stateroom category on select Norwegian sailings and you may be eligible to receive up an Ultimate Beverage package for 2, a Specialty Dining package, 250 minute Internet package and pre-paid service charges. Kids sail free on select dates. Applies to new reservations only. VALID ON SELECT FARE CODES ONLY. Not valid for mini-suite categories or MX category. Additional restrictions may apply please call to book.
  • Holiday Bonus: $100 FREE Onboard Spending!
  • Holiday Bonus: $100 FREE Onboard Spending!
    Book any category on a qualifying Holiday Norwegian sailings departing between 11/17/16 and 12/31/16 and we will give you a BONUS of $100 FREE onboard spending per stateroom occupied by two or more guests. Use it toward purchases at the spa, bars, shops, or shore excursions desk on the ship. Offer not applicable to categories IX, OX, BX, or, MX. May not be available on all rates or combinable with additional offers displayed online. New bookings only. Hurry - ends 11:59 pm EST on 8/31/16!
  • Rock Bottom Prices!
  • Rock Bottom Prices!
    Enjoy INCREDIBLE, rock-bottom savings on select Norwegian Cruise line sailings by booking a guarantee stateroom in categories IX, OX, BX, MX. These great savings are not combinable with any other cruise line offer.
Brochure price $1,999 – Save up to 70%
3.5 / 5  (1,160 reviews)

Norwegian Sun

Departing from: San Diego, California
Ports of Call: San Diego, California • Huatulco, Mexico • Puerto Chiapas (Tapachula), Mexico • Puerto Quetzal, Guatemala • Puntarenas, Costa Rica • Salaverry (Trujillo), Peru • Callao (Lima), Peru • Arica, Chile • Coquimbo (La Serena), Chile • Valparaiso (Santiago), Chile
interior from
$599
$35/night
oceanview from
$599
$35/night
balcony from
$1,049
$62/night
suite from
$1,699
$100/night
Bonus Offers Available:
  • CHOOSE 1: Free Drinks, Free Gratuities and More
  • CHOOSE 1: Free Drinks, Free Gratuities and More
    Call to book a studio or inside stateroom category on select Norwegian Cruise line sailings and you can choose between an Ultimate Beverage package for 2, a Specialty Dining package, a 250 minute internet package or pre-paid service charges. This offer is for new reservations only. NOT VALID FOR ALL FARES DISPLAYING ONLINE AND IS RESTRICTED TO CERTAIN FARE CODES. Not valid for category IX. Please call to book and for more information. Offer ends 11:59 pm EST on 10/02/16.
  • CHOOSE 2: Free Drinks, Free Gratuities and More
  • CHOOSE 2: Free Drinks, Free Gratuities and More
    Call to book an oceanview, balcony or mini-suite category stateroom on select Norwegian sailings and you can choose two of the following amenities: an Ultimate Beverage package for 2, a Specialty Dining package, a 250 minute internet package or pre-paid service charges. This offer is for new reservations only. NOT VALID FOR ALL FARES DISPLAYING ONLINE AND IS RESTRICTED TO CERTAIN FARE CODES. Not valid for categories OX, BX or MX. Please call to book and for more information. Offer ends 11:59 pm EST on 10/02/16.
  • Earn Unlimited Future Cruise Credits for Referrals!
  • Earn Unlimited Future Cruise Credits for Referrals!
    Each time you refer a new customer to us, we will give you a $50 Future Cruise Credit after their sailing departs. There is no limit to the number of Future Cruise Credits earned, and you can apply them toward your next booking with us. Simply have your referral call us to book, indicate that you recommended us, and provide us with your name and city/state or email address. Offer is not valid if the referred customer is traveling aboard the same sailing as you.
  • Haven & Suites Get 4: FREE Drinks, Dining & More!
  • Haven & Suites Get 4: FREE Drinks, Dining & More!
    Call to book a Haven Suite stateroom category on select Norwegian sailings and you may be eligible to receive up an Ultimate Beverage package for 2, a Specialty Dining package, 250 minute Internet package and pre-paid service charges. Kids sail free on select dates. Applies to new reservations only. VALID ON SELECT FARE CODES ONLY. Not valid for mini-suite categories or MX category. Additional restrictions may apply please call to book.
  • Rock Bottom Prices!
  • Rock Bottom Prices!
    Enjoy INCREDIBLE, rock-bottom savings on select Norwegian Cruise line sailings by booking a guarantee stateroom in categories IX, OX, BX, MX. These great savings are not combinable with any other cruise line offer.
  • Up To $500 Onboard Credit!
  • Up To $500 Onboard Credit!
    For a limited time only, receive up to $500 to spend onboard for liquor, beverages, dining, spa or shore excursions! Simply book a qualifying voyage online or over the phone! Offer is per stateroom, varies based on the price of cruise minus taxes and port charges, is not reflected in advertised prices, and will not exceed $500. Cruises between $750 - $1500 receive $25 OBC. Cruises between $1500 - $2500 receive $50 OBC. Cruises between $2500 - $3500 receive $75 OBC Cruises between $3500 - $4500 receive $100 OBC. Cruises between $4500 - $5500 receive $150 OBC. Cruises between $5500 - $7500 receive $200 OBC. Cruises between $7500 - $10000 receive $250 OBC. Cruises over $10,001 receive $500 OBC.
About South America
 

South America

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Terms & Conditions
Total cruise prices listed are samples in U.S. dollars of select stateroom category types as indicated and include non-commissionable fares. All prices and bonus offers are valid only for new individual bookings for select stateroom categories on select sailings aboard select cruise lines. Total cruise prices include government taxes and fees, airfare, and a non-refundable $24.99 processing fee per booking. Minimum hotel costs apply as follows: $250 for the $75 promo code, $300 for the $100 promo code, $400 for the $150 promo code, $475 for the $200 promo code, $550 for the $300 promo code, and $750 for the $500 promo code, $1,000 for the $750 hotel promo code and $1,250 for the $1,000 hotel promo code. Cancellation penalties, blackout dates, and other restrictions may apply. Total cruise prices and bonus offers vary by departure date and city, sailing, ship, and stateroom category selected and are subject to availability, capacity-controlled, limited by each cruise line, may not be combinable with other offers, and may be changed or withdrawn at any time without notice. All reservations must be made in U.S. dollars; restrictions may apply for non-U.S. residents. Full Terms & Conditions. Best Price Guarantee restrictions and instructions apply; see our Best Rate Guarantee Policy.

Special requirements
If you or a guest is pregnant or traveling with an infant child, or if there is a need to communicate a request for special meals, medical conditions or physical challenges, we ask that you please call 888-656-8184. Cruise Specialists are available 24 hours a day, 7 days a week. We will do everything we can to meet your needs and answer all of your questions.

Minimum age requirements may apply.
Free upgrade!
Book an eligible stateroom on any qualifying sailing and receive a free upgrade! In some cases, you'll be upgraded to a more desirable location aboard your ship. In other instances, you'll be upgraded to a stateroom with extra space and/or a better view. It's also possible that you might receive all of these benefits. Select your sailing date to see which upgrades are available.
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