Treat Yourself to a Fantastic South America Cruise

Experience the Pleasures of a South America Cruise

South America cruises with Orbitz offer the utmost in vacation fun and leisure, from one end of the continent to the other.

Set sail to the west coast city of Cartagena, Columbia, and experience the thrill of walking through the old, Spanish-colonial streets of downtown, immersed with authentic restaurants, shops and exquisite architecture. Colon, Panama offers an incredible shot of the Panama Canal, a 48-mile waterway which connects the Pacific and Atlantic Oceans. Arica, Chile is a port stationed on the Pacific coast and known for its beautiful and radiant beaches.

To the far east of South America, we’ll take you to the breathtaking beaches of Santos (Sao Paulo) or Ilhabela, the “Salt Capital” of Brazil. Discover the ancient artifacts and shipwrecked vessels resting at the bottom of the sea, just off the coast. For a more lively experience, visit Buzios and get down with their vivacious nightlife which includes discos, nightclubs and dynamic restaurants.

Don’t forget the beauty and charm of the country of Uruguay, a haven for spectacular cruise ports like Punta del Este and Montevideo; both exhibit extraordinary beaches, incredible surf and, on shore, a multitude of fun and exuberant tourist activities.

Book your South America cruise adventure with Orbitz, and you’re sure to take home memories of a vacation experience you will never forget.

SOUTH AMERICA CRUISE DEALS
SOUTH AMERICA CRUISE DEALS
Brochure price $2,899 – Save up to 59%
3.8 / 5  (237 reviews)

Zaandam

Departing from: Buenos Aires, Argentina
Ports of Call: Buenos Aires, Argentina • Montevideo, Uruguay • Port Stanley, Falkland Islands • Cruise Strait Of Magellan • Punta Arenas, Chile • Cruise Cockburn Channel • Cruise Beagle Channel • Cruise Glacier Alley • Ushuaia, Tierra Del Fuego, Argentina • Cruise Cape Horn • Cruise Canal Sarmiento • Cruise Chilean Fjords • Puerto Montt, Chile • Valparaiso (Santiago), Chile
interior from
$1,199
$86/night
oceanview from
$1,399
$100/night
balcony from
$2,499
$179/night
suite from
$4,599
$329/night
Bonus Offers Available:
  • Use Your Orbitz Rewards Visa: Earn 5% in Orbucks
  • Use Your Orbitz Rewards Visa: Earn 5% in Orbucks
    Book your next cruise with the Orbitz Rewards Visa Card and earn 5% in Orbucks! By land or by sea, this card comes with no fees - its the most rewarding travel card around. All qualifying Orbitz bookings earn 5% back in Orbucks on the total booking cost. All other purchases earn 2% back in Orbucks per dollar spent. Orbucks will be automatically deposited within two billing cycles.
  • CALL: Free Beverage Card, Gratuities and More!
  • CALL: Free Beverage Card, Gratuities and More!
    Call to book any stateroom on a qualifying Holland America sailing and we will give you a FREE $100 Beverage card and FREE prepaid gratuities (hotel service charges) for 1st and 2nd guests traveling in the same stateroom. Book a suite category and you will also receive 200 FREE internet minutes and up to $500 onboard spending. Not all fares displaying online qualify for this offer. Please call for more details and to book your cruise vacation. This offer ends 11:50 pm EST on 7/1/16.
  • Up To $750 Onboard Credit!
  • Up To $750 Onboard Credit!
    For a limited time only, receive up to $750 to spend onboard for liquor, beverages, dining, spa or shore excursions! Simply book a qualifying voyage online or over the phone! Offer is per stateroom, varies based on the price of cruise minus taxes and port charges, is not reflected in advertised prices, and will not exceed $750. Cruises between $750 - $999 receive $25 OBC. Cruises between $1,000 - $1,999 receive $50 OBC. Cruises between $2,000 - $2,999 receive $100 OBC. Cruises between $3,000 - $4,999 receive $200 OBC. Cruises between $5,000 - $9,999 receive $300 OBC. Cruises over $10,000 receive $750 OBC
  • CALL: Up to $100 FREE Onboard Spending!
  • CALL: Up to $100 FREE Onboard Spending!
    Call to book any stateroom on a qualifying Holland America sailing departing between 7/3/16 and 12/7/16, and we will give you up to $100 FREE onboard spending; amount varies by sailing! Hurry - limited space available.
  • Call For Reduced Booking Deposit!
  • Call For Reduced Booking Deposit!
    Call to book a new cruise at least 110 days prior to departure, and deposit only $50 per person for the first 2 passengers in a cabin, or $100 for a single occupant! This EXCLUSIVE offer covers most deposits up to $500, or up to $1,500 for select luxury cruises. Not valid on sailings requiring non-refundable deposits. Hurry: offer ends soon!
Brochure price $3,899 – Save up to 54%
3.5 / 5  (1,108 reviews)

Norwegian Sun

Departing from: Valparaiso (Santiago), Chile
Ports of Call: Valparaiso (Santiago), Chile • Puerto Montt, Chile • Puerto Chacabuco, Chile • Cruise Patagonic Channel • Cruise Chilean Fjords • Cruise Strait Of Magellan • Punta Arenas, Chile • Cruise Beagle Channel • Ushuaia, Tierra Del Fuego, Argentina • Cruise Cape Horn • Port Stanley, Falkland Islands • Puerto Madryn, Argentina • Montevideo, Uruguay • Buenos Aires, Argentina
interior from
$1,809
$129/night
oceanview from
$2,029
$145/night
balcony from
Call
suite from
Call
Bonus Offers Available:
  • Haven Suites Get 4: FREE Drinks, Dining & More!
  • Haven Suites Get 4: FREE Drinks, Dining & More!
    Call to book a Haven Suite stateroom category on select Norwegian sailings and you may be eligible to receive up an Ultimate Beverage package for 2, a Specialty Dining package, 250 minute Internet package and $50 per port shore excursion credit (max 4 ports). Applies to new reservations only made between 11/2/15 and 12/31/16. VALID ON SELECT FARE CODES ONLY. Not valid for mini-suite categories or MX category. Additional restrictions may apply please call to book. Hurry offer ends 11:59 pm EST on 12/31/16!
  • Use Your Orbitz Rewards Visa: Earn 5% in Orbucks
  • Use Your Orbitz Rewards Visa: Earn 5% in Orbucks
    Book your next cruise with the Orbitz Rewards Visa Card and earn 5% in Orbucks! By land or by sea, this card comes with no fees - its the most rewarding travel card around. All qualifying Orbitz bookings earn 5% back in Orbucks on the total booking cost. All other purchases earn 2% back in Orbucks per dollar spent. Orbucks will be automatically deposited within two billing cycles.
  • Up To $750 Onboard Credit!
  • Up To $750 Onboard Credit!
    For a limited time only, receive up to $750 to spend onboard for liquor, beverages, dining, spa or shore excursions! Simply book a qualifying voyage online or over the phone! Offer is per stateroom, varies based on the price of cruise minus taxes and port charges, is not reflected in advertised prices, and will not exceed $750. Cruises between $750 - $999 receive $25 OBC. Cruises between $1,000 - $1,999 receive $50 OBC. Cruises between $2,000 - $2,999 receive $100 OBC. Cruises between $3,000 - $4,999 receive $200 OBC. Cruises between $5,000 - $9,999 receive $300 OBC. Cruises over $10,000 receive $750 OBC
  • CALL to Choose 2: Dining package, Beverages, more
  • CALL to Choose 2: Dining package, Beverages, more
    Call to book an oceanview, balcony or mini-suite category stateroom on select Norwegian sailings and you can choose two of the following amenities: an Ultimate Beverage package for 2, a Specialty Dining package, a 250 minute internet package or $50 per port shore excursion credit (max 4 ports). This offer is for new reservations only made between 5/18/16 and 7/31/16. NOT VALID FOR ALL FARES DISPLAYING ONLINE AND IS RESTRICTED TO CERTAIN FARE CODES. Not valid for categories OX, BX or MX. Please call to book and for more information. Offer ends 11:59 pm EST on 7/31/16.
  • Choose Rock-Bottom Savings Or Free Drinks & More!
  • Choose Rock-Bottom Savings Or Free Drinks & More!
    Enjoy INCREDIBLE, rock-bottom savings on select Norwegian Cruise line sailings by booking a guarantee stateroom in categories IX, OX, BX, MX. These great savings are not combinable with any other cruise line offer. Or upgrade your cruise vacation experience by calling to book a non-guarantee stateroom and you may be able to choose an Ultimate Beverage package for 2, a Specialty Dining package, a 250 minute internet package or $50 per port shore excursion credit (max 4 ports). This offer is for new reservations only made between 5/18/16 and 7/31/16. NOT VALID FOR ALL FARES DISPLAYING ONLINE AND IS RESTRICTED TO CERTAIN FARE CODES. In some instances, you may have the option to select a reduced promotional fare OR your choice from the amenities above, but not both. Please call to book and for more information. Offer ends 11:59 pm EST on 7/31/16!
  • Call For Reduced Booking Deposit!
  • Call For Reduced Booking Deposit!
    Call to book a new cruise at least 110 days prior to departure, and deposit only $50 per person for the first 2 passengers in a cabin, or $100 for a single occupant! This EXCLUSIVE offer covers most deposits up to $500, or up to $1,500 for select luxury cruises. Not valid on sailings requiring non-refundable deposits. Hurry: offer ends soon!
Brochure price $1,999 – Save up to 55%
3.5 / 5  (1,108 reviews)

Norwegian Sun

Departing from: San Diego, California
Ports of Call: San Diego, California • Huatulco, Mexico • Puerto Chiapas (Tapachula), Mexico • Puerto Quetzal, Guatemala • Puntarenas, Costa Rica • Salaverry (Trujillo), Peru • Callao (Lima), Peru • Arica, Chile • Coquimbo (La Serena), Chile • Valparaiso (Santiago), Chile
interior from
$899
$53/night
oceanview from
$1,399
$82/night
balcony from
$2,129
$125/night
suite from
$3,899
$229/night
Bonus Offers Available:
  • Use Your Orbitz Rewards Visa: Earn 5% in Orbucks
  • Use Your Orbitz Rewards Visa: Earn 5% in Orbucks
    Book your next cruise with the Orbitz Rewards Visa Card and earn 5% in Orbucks! By land or by sea, this card comes with no fees - its the most rewarding travel card around. All qualifying Orbitz bookings earn 5% back in Orbucks on the total booking cost. All other purchases earn 2% back in Orbucks per dollar spent. Orbucks will be automatically deposited within two billing cycles.
  • Up To $750 Onboard Credit!
  • Up To $750 Onboard Credit!
    For a limited time only, receive up to $750 to spend onboard for liquor, beverages, dining, spa or shore excursions! Simply book a qualifying voyage online or over the phone! Offer is per stateroom, varies based on the price of cruise minus taxes and port charges, is not reflected in advertised prices, and will not exceed $750. Cruises between $750 - $999 receive $25 OBC. Cruises between $1,000 - $1,999 receive $50 OBC. Cruises between $2,000 - $2,999 receive $100 OBC. Cruises between $3,000 - $4,999 receive $200 OBC. Cruises between $5,000 - $9,999 receive $300 OBC. Cruises over $10,000 receive $750 OBC
  • CALL to Choose 2: Dining package, Beverages, more
  • CALL to Choose 2: Dining package, Beverages, more
    Call to book an oceanview, balcony or mini-suite category stateroom on select Norwegian sailings and you can choose two of the following amenities: an Ultimate Beverage package for 2, a Specialty Dining package, a 250 minute internet package or $50 per port shore excursion credit (max 4 ports). This offer is for new reservations only made between 5/18/16 and 7/31/16. NOT VALID FOR ALL FARES DISPLAYING ONLINE AND IS RESTRICTED TO CERTAIN FARE CODES. Not valid for categories OX, BX or MX. Please call to book and for more information. Offer ends 11:59 pm EST on 7/31/16.
  • Choose Rock-Bottom Savings Or Free Drinks & More!
  • Choose Rock-Bottom Savings Or Free Drinks & More!
    Enjoy INCREDIBLE, rock-bottom savings on select Norwegian Cruise line sailings by booking a guarantee stateroom in categories IX, OX, BX, MX. These great savings are not combinable with any other cruise line offer. Or upgrade your cruise vacation experience by calling to book a non-guarantee stateroom and you may be able to choose an Ultimate Beverage package for 2, a Specialty Dining package, a 250 minute internet package or $50 per port shore excursion credit (max 4 ports). This offer is for new reservations only made between 5/18/16 and 7/31/16. NOT VALID FOR ALL FARES DISPLAYING ONLINE AND IS RESTRICTED TO CERTAIN FARE CODES. In some instances, you may have the option to select a reduced promotional fare OR your choice from the amenities above, but not both. Please call to book and for more information. Offer ends 11:59 pm EST on 7/31/16!
  • Call For Reduced Booking Deposit!
  • Call For Reduced Booking Deposit!
    Call to book a new cruise at least 110 days prior to departure, and deposit only $50 per person for the first 2 passengers in a cabin, or $100 for a single occupant! This EXCLUSIVE offer covers most deposits up to $500, or up to $1,500 for select luxury cruises. Not valid on sailings requiring non-refundable deposits. Hurry: offer ends soon!
About South America
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Terms & Conditions
Total cruise prices listed are samples in U.S. dollars of select stateroom category types as indicated and include non-commissionable fares. All prices and bonus offers are valid only for new individual bookings for select stateroom categories on select sailings aboard select cruise lines. Total cruise prices include government taxes and fees, airfare, and a non-refundable $24.99 processing fee per booking. Minimum hotel costs apply as follows: $250 for the $75 promo code, $300 for the $100 promo code, $400 for the $150 promo code, $475 for the $200 promo code, $550 for the $300 promo code, and $750 for the $500 promo code, $1,000 for the $750 hotel promo code and $1,250 for the $1,000 hotel promo code. Cancellation penalties, blackout dates, and other restrictions may apply. Total cruise prices and bonus offers vary by departure date and city, sailing, ship, and stateroom category selected and are subject to availability, capacity-controlled, limited by each cruise line, may not be combinable with other offers, and may be changed or withdrawn at any time without notice. All reservations must be made in U.S. dollars; restrictions may apply for non-U.S. residents. Full Terms & Conditions. Best Price Guarantee restrictions and instructions apply; see our Best Rate Guarantee Policy.

Special requirements
If you or a guest is pregnant or traveling with an infant child, or if there is a need to communicate a request for special meals, medical conditions or physical challenges, we ask that you please call 888-656-8184. Cruise Specialists are available 24 hours a day, 7 days a week. We will do everything we can to meet your needs and answer all of your questions.

Minimum age requirements may apply.
Free upgrade!
Book an eligible stateroom on any qualifying sailing and receive a free upgrade! In some cases, you'll be upgraded to a more desirable location aboard your ship. In other instances, you'll be upgraded to a stateroom with extra space and/or a better view. It's also possible that you might receive all of these benefits. Select your sailing date to see which upgrades are available.
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